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Alpha-3 beta-4 nicotinic receptor : ウィキペディア英語版 | Alpha-3 beta-4 nicotinic receptor The alpha-3 beta-4 nicotinic receptor, also known as the α3β4 receptor, is a type of nicotinic acetylcholine receptor, consisting of α3 and β4 subunits. It is located in the autonomic ganglia〔(【引用サイトリンク】title=Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia )〕 and adrenal medulla,〔(【引用サイトリンク】title=Structural and functional diversity of native brain neuronal nicotinic receptors. )〕 where activation yields post- and/or presynaptic excitation.〔 As with other nicotinic acetylcholine receptors, the α3β4 receptor is pentameric (where m + n = 5 ). The exact subunit stoichiometry is not known and it is possible that more than one functional α3β4 receptor assembles in vivo with varying subunit stoichiometries. == Ligands ==
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