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Alpha-Naphthylthiourea
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Alpha-Naphthylthiourea : ウィキペディア英語版
Alpha-Naphthylthiourea

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α-Naphthylthiourea (ANTU) is an organosulfur compound with the formula C10H7NHC(S)NH2. This a white, crystalline powder although commercial samples may be off-white.〔Mackison, F. W., R. S. Stricoff, and L. J. Partridge, Jr. (eds.). NIOSH/OSHA - Occupational Health Guidelines for Chemical Hazards. DHHS(NIOSH) Publication No. 81-123 (3 VOLS). Washington, DC: U.S. Government Printing Office, Jan. 1981., p. 1-2〕〔O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 122〕〔NIOSH. NIOSH Pocket Guide to Chemical Hazards & Other Databases. U.S. Department of Health & Human Services, Public Health Service, Center for Disease Control & Prevention. DHHS (NIOSH) Publication No. 2001-145 (CD-ROM) August 2001〕 It is used as a rodenticide and as such is fairly toxic. Naphthylthiourea is available as 10% active baits in suitable protein- or carbohydrate-rich materials and as a 20% tracking powder.〔IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). p. V30 348 (1983)〕
==Synthesis==
Like other thioureas, ANTU can be prepared by several routes. The usual method is the reaction of 10H7NH3" TITLE="C10H7NH3">)Cl + NH4SCN → C10H7NHC(S)NH2 + NH3 + HCl
It is produced from the reaction of 1-naphthyl isothiocyanate with ammonia.
:Cl + NH4SCN → C10H7NHC(S)NH2 + NH3 + HCl
It is produced from the reaction of 1-naphthyl isothiocyanate with ammonia.
:[C10H7NCS + NH3 → C10H7NHC(S)NH2

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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