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Alpha-taxilin : ウィキペディア英語版 | Alpha-taxilin
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the ''TXLNA'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=200081 )〕 Interleukin-14 is a cytokine that controls the growth and proliferation of both normal and cancerous B cells. This molecule was also recently designated taxilin. IL-14 induces B-cell proliferation, inhibits antibody secretion, and expands selected B-cell subgroups. This interleukin is produced mainly by T cells and certain malignant B cells. == Gene ==
In murine models, two distinct transcripts are produced from opposite strands of the ''il14'' gene that are called IL-14α and IL-14β. The ''il14'' locus is near the gene for LCK on chromosome 1 in humans.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Alpha-taxilin」の詳細全文を読む
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