翻訳と辞書 Words near each other ・ Alstonia boonei ・ Alstonia breviloba ・ Alstonia constricta ・ Alstonia henryi ・ Alstonia iwahigensis ・ Alstonia longifolia ・ Alstonia macrophylla ・ Alstonia marquisensis ・ Alstonia penangiana ・ Alstonia pneumatophora ・ Alstonia rubiginosa ・ Alstonia rupestris ・ Alstonia scholaris ・ Alstonia spathulata ・ Alstonia venenata ・ Alstonine ・ Alstonite ・ Alstonville, New South Wales ・ Alstroemeria ・ Alstroemeria achirae ・ Alstroemeria psittacina ・ Alstroemeria pulchella ・ Alstroemeriaceae ・ Alström syndrome ・ Alström's warbler ・ Alströmergymnasiet ・ Alstugorna ・ Alsu Murtazina ・ Alsuma, Oklahoma ・ Alsunga Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Alstonine ： ウィキペディア英語版 Alstonine Alstonine is an indole alkaloid and putative antipsychotic constituent of various plant species including ''Alstonia boonei'', ''Catharanthus roseus'', ''Picralima nitida'', ''Rauwolfia caffra'' and ''Rauwolfia vomitoria''. In preclinical studies alstonine attenuates MK-801-induced hyperlocomotion, working memory deficit and social withdrawal. It also possesses anxiolytic-like effects in preclinical studies,〔 attenuates amphetamine-induced lethality and stereotypy as well as apomorphine-induced stereotypy,〔 and attenuates haloperidol-induced catalepsy. These effects appear to be mediated by stimulation of the 5-HT2C receptor. In addition, alstonine, similarly to clozapine, indirectly inhibits the reuptake of glutamate in hippocampal slices. Unlike clozapine however, the effect of which is abolished by the D2 receptor agonist apomorphine, alstonine requires 5-HT2A and 5-HT2C receptors to produce this effect, as it is abolished by antagonists of these receptors. Also unlike clozapine, alstonine lacks pro-convulsant activity in mice. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Alstonine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.