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Amanullin
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Amanullin is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the ''Amanita'' genus of mushrooms. The oral of amanullin is approximately 20 mg/kg in mice, however it is non-toxic in humans.
==Toxicology==
Like other amatoxins, amanullin is an inhibitor of RNA polymerase II. Amanullin has a species dependent and specific attraction to the enzyme RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme, effectively causing cytolysis of hepatocytes (liver cells).
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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