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Antrafenine
Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979.〔Manoury PM, Dumas AP, Najer H, Branceni D, Prouteau M, Lefevre-Borg FM. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates. Journal of Medicinal Chemistry. 1979 May;22(5):554-9.〕 It acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen,〔Leatham PA, Bird HA, Wright V, Seymour D, Gordon A. A double blind study of antrafenine, naproxen and placebo in osteoarthrosis. European Journal of Rheumatology and Inflammation. 1983;6(2):209-11.〕 but is not widely used as it has largely been replaced by newer drugs. == See also ==
* Phenylpiperazine
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Antrafenine」の詳細全文を読む
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