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Aphidicolin
|Section2= |Section3= }} Aphidicolin is a tetracyclic diterpene antibiotic isolated from the fungus, ''Cephalosporum aphidicola'' with antiviral and antimitotic properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. It blocks the cell cycle at early S phase. It is a specific inhibitor of DNA polymerase A,D in eukaryotic cells and in some viruses (vaccinia and herpesviruses) and an apoptosis inducer in HeLa cells. Natural aphidicolin is a secondary metabolite of the fungus ''Nigrospora oryzae''.〔(Aphidicolin product page ) from Fermentek〕 == Bibliography ==
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抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Aphidicolin」の詳細全文を読む
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