翻訳と辞書 Words near each other ・ Arabikadaloram ・ Arabikkadal ・ Arabikkatha ・ Arabinan endo-1,5-alpha-L-arabinosidase ・ Arabinda Muduli ・ Arabinda Rajkhowa ・ Arabineura ・ Arabineura khalidi ・ Arabinform ・ Arabinofuranan 3-O-arabinosyltransferase ・ Arabinofuranosylcytosine triphosphate ・ Arabinogalactan ・ Arabinogalactan endo-1,4-beta-galactosidase ・ Arabinogalactan protein ・ Arabinonate dehydratase ・ Arabinopyranosyl-N-methyl-N-nitrosourea ・ Arabinose ・ Arabinose isomerase ・ Arabinose-5-phosphate isomerase ・ Arabinosyl nucleosides ・ Arabinosyltransferase ・ Arabinoxylan ・ Arabis ・ Arabis (disambiguation) ・ Arabis aculeolata ・ Arabis alpina ・ Arabis armena ・ Arabis blepharophylla ・ Arabis caucasica ・ Arabis cypria Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Arabinopyranosyl-N-methyl-N-nitrosourea ： ウィキペディア英語版 Arabinopyranosyl-N-methyl-N-nitrosourea Arabinopyranosyl-''N''-methyl-''N''-nitrosourea, also known as Aranose, Aranoza - a cytostatic anticancer chemotherapeutic drug of an alkylating type. Chemically it is a nitrosourea derivative. It was developed in Soviet Union in the 1970s. It was claimed by its developers that its advantages over other nitrosoureas are a relatively low hematological toxicity (compared to other nitrosoureas available at that time) and a wider therapeutic index, which allows for its outpatient administration. == History == It was first synthesized in late 1970s in the Laboratory of Organic Synthesis of Soviet Cancer Research Institute (which belonged to Academy of Medical Sciences of the USSR). Its first clinical trials in USSR were conducted in the late 1980s. Those trials confirmed its potential clinical efficacy in melanoma and better relative safety & improved tolerability over other nitrosourea antineoplastic compounds available at that time. In 1996 the compound obtained an Russian Pharmacologic Committee (a Russian analog of the U.S. Food and Drug Administration (FDA) and EMA in the European Community) regulatory approval for its use in melanoma under the trade name Aranoza. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Arabinopyranosyl-N-methyl-N-nitrosourea」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.