翻訳と辞書 Words near each other ・ Asparn an der Zaya ・ Asparrena ・ Aspartame ・ Aspartame controversy ・ Aspartame-acesulfame salt ・ Aspartate 1-decarboxylase ・ Aspartate 4-decarboxylase ・ Aspartate ammonia-lyase ・ Aspartate carbamoyltransferase ・ Aspartate dehydrogenase ・ Aspartate kinase ・ Aspartate N-acetyltransferase ・ Aspartate protease ・ Aspartate racemase ・ Aspartate receptor ・ Aspartate transaminase ・ Aspartate-semialdehyde dehydrogenase ・ Aspartate—ammonia ligase ・ Aspartate—ammonia ligase (ADP-forming) ・ Aspartate—phenylpyruvate transaminase ・ Aspartate—prephenate aminotransferase ・ Aspartate—tRNA ligase ・ Aspartate—tRNA(Asn) ligase ・ Aspartic acid ・ Aspartic acid (data page) ・ Aspartic alpha-decarboxylase ・ Aspartoacylase ・ Aspartyl aminopeptidase ・ Aspartylglucosamine ・ Aspartylglucosaminidase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Aspartate transaminase ： ウィキペディア英語版 Aspartate transaminase Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (). AST catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, and red blood cells. Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels. ==Function== Aspartate transaminase catalyzes the interconversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate. Aspartate (Asp) + α-ketoglutarate ↔ oxaloacetate + glutamate (Glu) As a prototypical transaminase, AST relies on PLP (Vitamin B6) as a cofactor to transfer the amino group from aspartate or glutamate to the corresponding ketoacid. In the process, the cofactor shuttles between PLP and the pyridoxamine phosphate (PMP) form. The amino group transfer catalyzed by this enzyme is crucial in both amino acid degradation and biosynthesis. In amino acid degradation, following the conversion of α-ketoglutarate to glutamate, glutamate subsequently undergoes oxidative deamination to form ammonium ions, which are excreted as urea. In the reverse reaction, aspartate may be synthesized from oxaloacetate, which is a key intermediate in the citric acid cycle. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Aspartate transaminase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.