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Atovaquone (alternative spelling: atavaquone) is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. It is manufactured in the US in the liquid form, or oral suspension, under the brand name Mepron.〔(Mepron )〕 ==Uses== Atovaquone is a medication used to treat or prevent: # For pneumocystis pneumonia (PCP), it is used in mild cases, although it is not approved for treatment of severe cases. # For toxoplasmosis, the medication has antiparasitic and therapeutic effects. # For malaria, it is one of the two components (along with proguanil) in the drug Malarone. Malarone has fewer side effects and is more expensive than mefloquine.〔( Malarone: New Malaria Medication With Fewer Side-effects )〕 Resistance has been observed. # For babesia, it is often used in conjunction with oral azithromycin. Trimethoprim-sulfamethoxazole (TMP-SMX, Bactrim) is generally considered first-line therapy for PCP or toxoplasmosis. However, atovaquone may be used in patients who cannot tolerate, or are allergic to, sulfonamide medications such as TMP-SMX. In addition, atovaquone has the advantage of not causing myelosuppression, which is an important issue in patients who have undergone bone marrow transplantation. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Atovaquone」の詳細全文を読む スポンサード リンク
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