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Azapride
Azapride is the azide derivative of the dopamine antagonist clebopride. It is an irreversible dopamine antagonist.〔''European Journal of Biochemistry'' 1984, 145(2), p.273〕 It was synthesised directly from clebopride, in order to label D2 dopamine receptors selectively.〔Niznik HB, Guan JH, Neumeyer JL, Seeman P. (1985) 'A photoaffinity ligand for dopamine D2 receptors: azidoclebopride.', Mol Pharmacol.〕 Azapride has been tested for its usefulness as a photoaffinity probe for dopamine receptors. Some scientists believe it will be of great value for further molecular characterization and purification of dopamine receptors.〔Wouters W, Van Dun J, Laduron PM.(1984),'Photoaffinity labelling of dopamine receptors. Synthesis and binding characteristics of azapride.', Eur J Biochem. 〕 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Azapride」の詳細全文を読む
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