|
An azole is a class of five-membered nitrogen heterocyclic ring compounds containing at least one other non-carbon atom of either nitrogen, sulfur, or oxygen.〔 〕 The parent compounds are aromatic and have two double bonds; there are successively reduced analogs (azolines and azolidines) with fewer. One, and only one, lone pair of electrons from each heteroatom in the ring is part of the aromatic bonding in an azole. Names of azoles maintain the prefix upon reduction (e.g., pyrazoline, pyrazolidine). The numbering of ring atoms in azoles starts with the heteroatom that is not part of a double bond, and then proceeds towards the other heteroatom. Imidazole and other six-membered aromatic heterocyclic systems with two nitrogens are extremely common in nature and form the core of many biomolecules ==Compound classes== Azoles * 1 nitrogen atom (but it only includes one nitrogen and no other heteroatom) * *pyrrole * 2 or more nitrogen atoms * *pyrazole * *imidazole, included in histidine * *triazole, included in Ribavirin * *tetrazole * *pentazole * 1 nitrogen atom and 1 oxygen atom * * oxazole * * isoxazole * 1 nitrogen atom and 1 sulfur atom * * thiazole * * isothiazole A "dioxole" is a similar compound with two oxygen atoms in a five membered ring. Dioxolane is a derivative of dioxole. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Azole」の詳細全文を読む スポンサード リンク
|