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BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the ''BAP1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8314 )〕 ''BAP1'' encodes an 80.4 kDa nuclear-localizing protein with a ubiquitin carboxy-terminal hydrolase (UCH) domain that gives BAP1 its deubiquitinase activity.〔 Recent studies have shown that ''BAP1'' and its fruit fly homolog, (''Calypso'' ), are members of the polycomb-group proteins (PcG) of highly conserved transcriptional repressors required for long-term silencing of genes that regulate cell fate determination, stem cell pluripotency, and other developmental processes. == Nomenclature == BAP1 is also known as: * UniProt name: (Ubiquitin carboxyl-terminal hydrolase BAP1 ) * ubiquitin carboxyl-terminal hydrolase like-2 (UCHL2) * human cerebral protein 6 (hucep 6) * human cerebral protein-13 (hucep-13) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「BAP1」の詳細全文を読む スポンサード リンク
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