翻訳と辞書 Words near each other ・ BCKDHA ・ BCKDHB ・ BCKDK ・ BCL ・ BCL Molecular ・ BCL Springs ・ Bcl-2 ・ Bcl-2 family ・ Bcl-2 homologous antagonist killer ・ Bcl-2-associated death promoter ・ Bcl-2-associated X protein ・ Bcl-2-interacting killer ・ BCL-6 corepressor ・ Bcl-x interacting domain ・ Bcl-xL ・ BCL10 ・ BCL11A ・ BCL11B ・ BCL2-like 1 (gene) ・ BCL2-related protein A1 ・ BCL2L10 ・ BCL2L11 ・ BCL2L12 ・ BCL2L13 ・ BCL2L14 ・ BCL2L2 ・ BCL3 ・ BCL6 ・ BCL6B ・ BCL9 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク BCL10 ： ウィキペディア英語版 BCL10 B-cell lymphoma/leukemia 10 is a protein that in humans is encoded by the ''BCL10'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8915 )〕 Like BCL2, BCL3, BCL5, BCL6, BCL7A, and BCL9, it has clinical significance in lymphoma. == Function == This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with the paracaspase MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.〔 Bcl10 has been shown to be functionally conserved all the way back to zebrafish 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「BCL10」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.