翻訳と辞書 Words near each other ・ Bcl-2 family ・ Bcl-2 homologous antagonist killer ・ Bcl-2-associated death promoter ・ Bcl-2-associated X protein ・ Bcl-2-interacting killer ・ BCL-6 corepressor ・ Bcl-x interacting domain ・ Bcl-xL ・ BCL10 ・ BCL11A ・ BCL11B ・ BCL2-like 1 (gene) ・ BCL2-related protein A1 ・ BCL2L10 ・ BCL2L11 ・ BCL2L12 ・ BCL2L13 ・ BCL2L14 ・ BCL2L2 ・ BCL3 ・ BCL6 ・ BCL6B ・ BCL9 ・ BCLAF1 ・ BCLUW Community School District ・ BCM ・ BCM Classification ・ BCM Gravelines ・ BCM theory ・ BCMA Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク BCL2L12 ： ウィキペディア英語版 BCL2L12 Bcl-2-like protein 12 is a protein that in humans is encoded by the ''BCL2L12'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83596 )〕 The protein encoded by this gene belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.〔 Bcl2L12 expression is upregulated in most human glioblastomas. Expression of Bcl2L12 results in resistance to apoptosis. Bcl2L12 directly neutralizes caspase-7 (CASP7) and indirectly neutralizes caspase-3 (CASP3) by an indirect mechanism. Both caspase enzymes are known to play essential roles in the execution phase of apoptosis. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「BCL2L12」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.