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BHLHE41 : ウィキペディア英語版
BHLHE41

"Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes, as the name implies, a basic helix-loop-helix protein in various tissues of both humans and mice.〔
(【引用サイトリンク】 BHLHE41 basic helix-loop-helix family, member e41 (Homo sapiens (human) ) )〕

(【引用サイトリンク】 Bhlhe41 basic helix-loop-helix family, member e41 (Mus musculus (house mouse) ) )〕〔
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(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79365 )

It also known as DEC2, hDEC2, and SHARP1, and was previously known as "basic helix-loop-helix domain containing, class B, 3", or BHLHB3.〔
(【引用サイトリンク】 Basic Helix-Loop-Helix Family, Member E41 )
== Function ==

This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock.〔
In mice lacking SHARP1 and SHARP2, IGF-2 is elevated and so memory consolidation is enhanced.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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