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BODIPY
BODIPY, abbreviation for ''boron-dipyrromethene'', is a class of fluorescent dyes. It is composed of dipyrromethene complexed with a disubstituted boron atom, typically a BF2 unit.〔Alfred Treibs und Franz-Heinrich Kreuzer. Difluorboryl-Komplexe von Di- und Tripyrrylmethenen. Justus Liebigs Annalen der Chemie 1968, 718 (1): 208-223; (BODIPY Dye Series )〕 The IUPAC name for the BODIPY core is ''4,4-difluoro-4-bora-3a,4a-diaza-s-indacene''. Due to instability of the required unsubstituted dipyrromethene precursor, the unsubstituted BODIPY dye had not been prepared until 2009. Three independent groups reported different syntheses of the title compound. ==Properties== BODIPY dyes are notable for their uniquely small Stokes shift, high, environment-independent fluorescence quantum yields, often approaching 100% even in water, sharp excitation and emission peaks contributing to overall brightness, and high solubility in many organic solvents. The combination of these qualities makes BODIPY fluorophore an important tool in a variety of imaging applications. The position of the absorption and emission bands remain almost unchanged in solvents of different polarity as the dipole moment and transition dipole are orthogonal to each other.
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