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BOSC23
BOSC23 is a human kidney cell line developed by Prof. David Baltimore 〔http://www.bio.net/bionet/mm/methods/2000-December/086646.html〕 derived from 293T cells 〔Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. vol.90, pp.8392-8396, September 1993〕 and can be grown and transfected as the way for 293T.〔http://celljunctions.med.nyu.edu/lab/notprivate/methods-html/RETROVIRUS.html〕 This cell line is a model for cancer research which doesn't have Src protein.〔Goh YM, Cinghu S, Hong ETH et al. Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm. The Journal of Biochemistry vol.285, no.13, pp.10122-10129, March 2010〕 ==References==
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