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・ Brce
・ Brckovljani
・ BRCT domain
・ BRCW Type 2
・ BRD
・ BRD (Germany)
・ BRD Arad Challenger
・ BRD Brașov Challenger
・ BRD Timișoara Challenger
・ BRD Tower
・ BRD Tower Bucharest
・ BRD Tower Cluj-Napoca
・ BRD Trilogy
・ BRD – Groupe Société Générale
・ BRD2
BRD4
・ BRD7
・ BRD8
・ BRD9
・ Brda
・ Brda (Drvar)
・ Brda (Kupres)
・ Brda (river)
・ Brda (Rogatica)
・ Brda (Srebrenik)
・ Brda (Trnovo)
・ Brda dialect
・ Brda, Bugojno
・ Brda, Donji Vakuf
・ Brda, Konjic


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BRD4 : ウィキペディア英語版
BRD4

Bromodomain-containing protein 4 is a protein that in humans is encoded by the ''BRD4'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23476 )
BRD4 is a member of the BET (bromodomain and extra terminal domain) family, which also includes BRD2, BRD3, and BRDT. BRD4, similar to other BET family members, contains two bromodomains that recognize acetylated lysine residues. BRD4 also has an extended C-terminal domain with little sequence homology to other BET family members.〔
== Structure ==

The two bromodomains in BRD4, termed BD1 and BD2, consist of 4 alpha-helices linked by 2 loops. The ET domain structure is made up of 3 alpha-helices and a loop. The C-terminal domain of BRD4 has been implicated in promoting gene transcription through interaction with the transcription elongation factor P-TEFb and RNA polymerase II.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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