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Batanopride : ウィキペディア英語版
Batanopride

Batanopride (BMY-25,801) is an antiemetic drug of the benzamide class which acts as a selective 5-HT3 receptor antagonist.〔Gylys JA, Wright RN, Nicolosi WD, Buyniski JP, Crenshaw RR. BMY-25801, an antiemetic agent free of D2-dopamine receptor antagonist properties. ''Journal of Pharmacology and Experimental Therapeutics''. 1988 Mar;244(3):830-7. PMID 2978041〕 It was trialled to reduce nausea during cancer chemotherapy, but was never approved for medical use due to dose-limiting side effects including hypotension and long QT syndrome.〔Fleming GF, Vokes EE, McEvilly JM, Janisch L, Francher D, Smaldone L. Double-blind, randomized crossover study of metoclopramide and batanopride for prevention of cisplatin-induced emesis. ''Cancer Chemotherapy and Pharmacology''. 1991;28(3):226-7. PMID 1855280〕
== References ==




抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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