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|Section2= |Section3= }} Benzamil or benzyl amiloride is a potent blocker of the ENaC channel 〔cite journal | last = Chalfant | first = M.L. | year = 1995 | title = Regulation of epithelial Na+ channels from M-1 cortical collecting duct cells | journal= AMERICAN JOURNAL OF PHYSIOLOGY-RENAL FLUID AND ELECTROLYTE PHYSIOLOGY | volume=271 | pages=f861-f870 〕 and also a sodium-calcium exchange blocker.〔 〕 It is a potent analog of amiloride, and is marketed as the hydrochloride salt (benzamil hydrochloride). As amiloride, benzamil has been studied as a possible treatment for cystic fibrosis, although with disappointing results. ==Structure== Benzamil is a benzyl group-containing analog of amiloride. Like amiloride, it is a guanidinium group-containing pyrazine derivative. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Benzamil」の詳細全文を読む スポンサード リンク
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