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|Section5= |Section6= |Section7= |Section8= }} Benzestrol is an organic compound that was formerly used as a non-steroidal estrogen antagonist.〔(【引用サイトリンク】url=http://www.chemicalbook.com/ChemicalProductProperty_EN_CB31178097.htm )〕 It is part of a family of compounds called DES drugs with the family leader called diethylstilbestrol. These drugs were used extensively in the mid-1900s and were finally banned by the FDA due to them causing tumors in the children of women who used them.〔(【引用サイトリンク】 DES History )〕 ==Uses== Benzestrol and other DES drugs were used as a synthetic estrogen in order to prevent premature births.〔 Based on the idea that premature births happened because the mother did not produce enough estrogen on her own, doctors prescribed benzestrol to mothers in order to increase their estrogen levels. Studies have been done in the past on normal, mature and castrate female rats. Benzestrol produced the same type of estrus in the castrate rat when injected at 0.8 to 1.0 micrograms as when the rat was injected with 2.0 to 2.5 micrograms of estrone. This is significant because less benzestrol could be used to produce the same effect as estrone in increasing estrogen production. It has been used in the past as a nonsteroidal estrogen antagonist. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Benzestrol」の詳細全文を読む スポンサード リンク
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