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Bepotastine : ウィキペディア英語版
Bepotastine

Bepotastine (Talion, Bepreve) is a 2nd-generation antihistamine. It was approved in Japan for use in the treatment of allergic rhinitis and urticaria/pruritus in July 2000 and January 2002, respectively. It is currently marketed in the United States under the brand-name Bepreve, by ISTA Pharmaceuticals.
== Pharmacology ==

Bepotastine is available as an ophthalmic solution and oral tablet. It is a direct H1-receptor antagonist that inhibits the release of histamine from mast cells. The ophthalmic formulation has shown minimal systemic absorption, between 1 and 1.5% in healthy adults. Common side effects are eye irritation, headache, unpleasant taste, and nasopharyngitis.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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