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Words near each other
・ Bid Kaj
・ Bid Kalmeh
・ Bid Kaneh
・ Bid Kaneh explosion
・ Bid Kard Gam
・ Bid Karz
・ Bid Khal
・ Bid Khan
・ Bid Kheyri
・ Bid Kheyri, Bardsir
・ Bid Kheyri, Jiroft
・ Bicycling with Molière
・ Bicyclo(2.2.1)heptane-2-carbonitrile
・ Bicyclobutane
・ Bicyclogermacrene synthase
Bicyclononyne
・ Bicyclopropenyl
・ Bicycloundecane
・ Bicyclus
・ Bicyclus abnormis
・ Bicyclus albocincta
・ Bicyclus alboplaga
・ Bicyclus amieti
・ Bicyclus analis
・ Bicyclus angulosa
・ Bicyclus anisops
・ Bicyclus anynana
・ Bicyclus auricruda
・ Bicyclus aurivillii
・ Bicyclus brakefieldi


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Bicyclononyne : ウィキペディア英語版
Bicyclononyne

BCN, also known as bicyclo()nonyne, is a copper-free click chemistry probe that enables highly efficient and completely orthogonal bioconjugation to complex macromolecules including peptides, nucleic acids and proteins, including monoclonal antibodies. The most recent and powerful application of this technology has been in the field of antibody-drug conjugates which results in targeted cancer therapeutics that have an improved therapeutic index, meaning they are safer and more effective. Amongst its most notable features, BCN is ideally suited for aqueous bioconjugations due to its high reactivity with its azide counterpart combined with its high hydrophilicity, relative to all other metal-free click chemistry probes. See also "copper-free click chemistry". Commercial use of BCN is proprietary to Netherlands-based biotechnology company, (Synaffix BV ).
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Bicyclononyne」の詳細全文を読む



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