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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Bio-FET ： ウィキペディア英語版 Bio-FET Field effect transistor based biosensor (Bio-FET) is a field-effect transistor that is gated by biological molecules. When biological molecules bind to the FET gate they can change the gate charge distribution resulting in a change in conductance of the FET channel.〔Brand U, Brandes L, Koch V, Kullik T, Reinhardt B, Rüther F, Scheper T, Schügerl K, Wang S, Wu X: Monitoring and control of biotechnological production processes by Bio-FET-FIA-sensors, Appl Microbiol Biotechnol., 1991 Nov;36(2):167-72.〕 A Bio-FET consists of two main compartments: one is the biological recognition element and the other is the field effect transistor (e.g. ISFET).〔Joonhyung Lee, Piyush Dak, Yeonsung Lee, Heekyeong Park, Woong Choi, Muhammad A. Alam, Sunkook Kim: Two-dimensional Layered MoS2 Biosensors Enable Highly Sensitive Detection of Biomolecules, Sci Rep., 2014; 4: 7352.〕 == Function of Bio-FET == Bio-FETs couple a semiconductor device to a bio-sensitive layer that detects bio-molecules such as nucleic acids.〔Alena Bulyha, Clemens Heitzinger and Norbert J Mauser: Bio-Sensors: Modelling and Simulation of Biologically Sensitive Field-Effect-Transistors, ERCIM News, 04,2011.〕 A Bio-FET system consists of a semiconducting transducer separated by an insulator layer (e.g. SiO2) from the biological recognition element (e.g. receptors or probe molecules). A Bio-FET also consists of a transducer immobilized to the surface which contains the target molecule called analyte. Once the analyte binds to the recognition element, the charge distribution at the surface will change, triggering a change in the electrostatic potential of the semiconductor. The transistor controls the electron flow in the channel using two electrodes, which are called source and drain.〔Matsumoto A, Miyahara Y: Current and emerging challenges of field effect transistor based bio-sensing, Nanoscale., 2013 Nov 21;5(22):10702-18. doi: 10.1039/c3nr02703a. Epub 2013 Sep 25.〕 As a result, the conductance of the semiconductor changes, which can be measured. This change of conductance directly yields the concentration.〔 The current flow between the source and drain is controlled by the gate.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bio-FET」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.