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Biomatrica
Biomatrica is a United States-based biotechnology company that develops biological stabilizers for the purpose of expanding the availability and accuracy of medical diagnostics. Specifically, the company focuses on improving the stability of biological materials, such as DNA, RNA, proteins, and cells, across the diagnostic workflow, from patient samples to diagnostic test reagents. Biomatrica scientists have developed alternatives to existing preservation technologies, such as cold storage and lyophilization (freeze-drying), to prevent degradation of perishable biological materials. Biomatrica's technologies are used in applications such as pre-analytic sample collection, diagnostic assays, biobanking, forensics, and basic research.
==History==
Biomatrica was founded by scientists, Judy Müller-Cohn, PhD, and Rolf Müller, PhD, in 2004. Prior to founding Biomatrica, both had worked many years in San Diego’s biotechnology industry. Judy Müller-Cohn was previously Director of Business Development at Digital Gene Technologies and a scientist at Mycogen/ Dow Agrosciences. Rolf Muller had been a visiting Scientist and Director of Assay Development and High Throughput Screening for the HIV Core Program Project Grant at San Diego’s prestigious Scripps Research Institute. Prior to that, he served as a scientific director at HK Pharmaceuticals and Digital Gene Technologies, as well as a scientist at the Salk Institute studying cell signaling and viral based gene therapy approaches.
Biomatrica initially developed ambient temperature storage reagents for DNA and RNA. The company’s core technology was inspired by the phenomenon of anhydrobiosis, the ability of some organisms to hibernate in a desiccated state during dry periods, and then reanimate upon contact with water.〔 Focusing their studies on microscopic, desert-dwelling creatures called Tardigrades, which undergo anhydrobiosis for up to 120 years, Biomatrica scientists identified how to chemically mimic the mechanism of anhydrobiosis. According to Rolf Müller, “What we create(d) is a thermostable, dissolvable glass that packages every single molecule in a sample.” Following stabilization at room temperature with Biomatrica's chemical reagents, biological specimens could be rehydrated for subsequent studies with the addition of a few drops of water.
Since 2012, the company has become increasingly focused on its pre-analytic collection and assay stabilization service businesses, described below.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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