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Bionovo
Bionovo (NASDAQ: BNVI.OB) was an American biotechnology company focused on the discovery and development of botanically derived treatments for women's health and cancer based in Emeryville, California. The company had two drug candidates in U.S. Food and Drug Administration (FDA) clinical trials- Menerba (formerly known as MF101) a selective estrogen receptor beta agonist for hot flashes associated with menopause and Bezielle (formerly BZL101) for advanced breast cancer. The company has ceased activity and its stock, although still listed, not moved from 0,00 USD since the end of 2012.〔(Yahoo Finance )〕 No statement has been made by the management, nor any indication has been given that the company is still active. The last press statement was about the sell of all the technical equipment and lay off of 90% of the staff. In short words, the company is as good as bankrupted and shut down, although the management never officially admitted it.〔(Bizjournal.com, Mar 13, 2012 )〕
==Discovery and development platform==
Bionovo used traditional Chinese medicine (TCM) as its discovery engine, isolating, purifying and testing potent active ingredients from herbs and other botanicals, then formulating them into products which can be packaged as powders or pills for easy use by patients.
The company identified the active chemical components underpinning the mechanism of action for all of their lead drug candidates, and in some cases, has developed synthetic methods of production. They are developing their drugs in accordance with the U.S. FDA's botanical drug guidelines.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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