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Biperiden : ウィキペディア英語版
Biperiden

Biperiden is a medication used to treat Parkinson disease. It is of the anticholinergic type. The original brand name, which still exists and is manufactured by BASF/Knoll Pharma, is Akineton. Generics are available worldwide, one of them is Dekinet manufactured by Rafa Laboratories.
== Medical uses ==
Biperiden is used for the adjunctive treatment of all forms of Parkinson's disease and for reduced sweating in methadone users (postencephalitic, idiopathic, and arteriosclerotic). It seems to exert better effects in the postencephalitic and idiopathic than in the arteriosclerotic type.
Biperiden is also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.
It relieves muscle rigidity, reduces abnormal sweating related with Clozapine and Methadone use and salivation, improves abnormal gait, and to lesser extent, tremor.
In its role as a synthetic acetylcholine antagonist, biperiden has been analyzed as an alternative anticonvulsant for usage in the treatment of intoxication by organophosphorus nerve agents, such as sarin.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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