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Brevianamide : ウィキペディア英語版
Brevianamide

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Brevianamides are a class of indole alkaloids produced as secondary metabolites of fungi in the genus ''Penicillium'' and ''Aspergillus''. Structurally similar to paraherquamides, they are a small class compounds that contain a bicyclo()diazoctane ring system. One of the major secondary metabolites in ''Penicillium'' spores, they are responsible for inflammatory response in lung cells.
==History==
Originally isolated from ''Pennicillum compactum'' in 1969, brevianamide A has shown insecticidal activity.〔 Further studies showed that a minor secondary metabolite, brevianamide B, has an epimeric center at the spiro-indoxyl quaternary center. Both were found to fluoresce under long-wave ultraviolet radiation. Furthermore, under irradaton, brevianamide A has been shown to isomerize to brevianamide B.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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