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Butenafine : ウィキペディア英語版
Butenafine

Butenafine hydrochloride is a synthetic benzylamine antifungal, marketed under the trade names Mentax, Butop (India) and is the active ingredient in Schering-Plough's Lotrimin Ultra. It is structurally related to synthetic allylamine antifungals such as terbinafine.
== Medical uses ==
Butenafine is indicated for the topical treatment of tinea (pityriasis) versicolor due to M. furfur, as well as athlete’s foot (''Tinea pedis''), ringworm (''Tinea corporis'') and jock itch (''Tinea cruris'') due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
It also displays superior activity against Candida albicans than terbinafine and naftifine. Butenafine demonstrates low minimum inhibitory concentrations against ''Cryptococcus'' and ''Aspergillus''.
There is some evidence that it is effective against dermatophyte infections of the toenails, but needs to be applied daily for prolonged periods (at least one year).〔(The Cochrane Library: Topical treatments for fungal infections of the skin and nails of the foot, 2009. )〕
Butenafine is typically available as a 1% topical cream.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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