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C11orf1
Chromosome 11 open reading frame one, also known as C11orf1, is a protein-coding gene.〔(【引用サイトリンク】 url =http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64776 )〕 It has been found by yeast two hybrid screen to bind to SETDB1 a histone protein methyltranferase enzyme. SETDB1 has been implicated in Huntington's disease, a neurodegenerative disorder. C11orf1 is a nuclear protein with unknown function but has been shown to show preferential expression in some disease states in microarray data. == Species distribution ==
C11orf1 shows conservation through mammals and orthologs can be found in sea squirts and sea anemone. The below table shows some orthologs found using BLAST.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「C11orf1」の詳細全文を読む
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