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C5orf3
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C5orf3 : ウィキペディア英語版
C5orf3

C5orf3 (chromosome 5 open reading frame 3) is a gene on chromosome 5 in humans that encodes a protein FAM114A2. This protein has a function that is not well known. C5orf3 is, however, highly conserved in mammals with homologs both in fungi and plants.
==Protein==
The c5orf3 protein is 505 amino acids long〔(Homo sapiens family with sequence similarity 114, member A2 (FAM114A2) - Nucleotide - NCBI )〕 with a molecular weight of 55.5 kdal and an isoelectric point of 4.66.〔Biology workbench: http://seqtool.sdsc.edu/CGI/BW.cgi#!〕 It is predicted to stay in the nucleus after translation 〔(PSORT WWW Server )〕
There is evidence that c5orf3 interacts with another protein of unknown function from chromosome 5, c5orf4 〔STRING: http://string-db.org/newstring_cgi/show_network_section.pl.〕
This protein is thought to include a P loop 〔http://string-db.org/newstring_cgi/show_textmining_evidence.pl.〕 that suggests a role in ATP- and/or GTP-binding

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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