翻訳と辞書
Words near each other
・ Camitocomus nodosus
・ CAMIVA
・ Camixaima beraba
・ Camizunzo
・ Camiña
・ Camjac
・ CAMK
・ CAMK1
・ CAMK1D
・ CAMK2A
・ CAMK2B
・ CAMK2D
・ CAMK2G
・ CAMK4
・ CAMKK1
CAMKK2
・ Camko City
・ CAML
・ Caml
・ Caml Lights
・ CaMLA
・ CaMLA English Placement Test
・ Camlachie
・ Camlann Medieval Village
・ Camlaren Mine
・ Camless
・ Camlet
・ Camlet Way
・ Camley Street Natural Park
・ Camlez


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

CAMKK2 : ウィキペディア英語版
CAMKK2

Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the ''CAMKK2'' gene.〔〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10645 )
==Function==
The product of this gene belongs to the serine/threonine-specific protein kinase family, and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4.〔
CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus. It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs, through reduction in downstream signalling pathways and mu opioid receptor downregulation. Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「CAMKK2」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.