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CCDC176
Basal body-orientation factor 1 (BBOF1) is a protein that in humans is encoded by the gene CCDC176, which is located on the plus strand of chromosome 14 at 14q24.3.〔http://www.ncbi.nlm.nih.gov/gene/?term=NP_079333〕 CCDC176 is neighbored by ALDH6A1 and ENTPD5 at the same locus.〔http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=c14orf45&submit=Go〕 The mRNA is 3123 base pairs long and has 12 exons, the protein is 529 amino acids long and has a molecular weight of 61987 Da and a predicted isoelectric point of 9.07 in humans.〔http://www.phosphosite.org/proteinAction.do?id=17259&showAllSites=true〕 ==Homology and evolution==
CCDC176 has no known paralogs and is orthologous in primates, mammals, birds, reptiles, amphibians, fish, all the way back to invertebrates, a fungi parasite and a proteobacteria. The domain found to be homologous is the DUF4515, a domain of unknown function.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CCDC176」の詳細全文を読む
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