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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク CCM1 ： ウィキペディア英語版 KRIT1 Krev interaction trapped protein 1 is a protein that in humans is encoded by the ''CCM1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=889 )〕 This gene contains 16 coding exons and is located on chromosome 7q21.2. Loss of function mutations in ''CCM1'' result in the onset of Cerebral cavernous malformation. Cerebral cavernous malformations (CCMs) are vascular malformations in the brain and spinal cord made of dilated capillary vessels. == Interactions == The normal CCM1 protein, KRIT1 (Krev Interaction Trapped), is 736 amino acids in length and has a variety of functions. KRIT1 has been shown to interact with multiple signaling pathways including; ITGB1BP1., reactive oxygen species, cell death, and angiogenesis. Related to the CCM illness, this protein is required for maintaining the structural integrity of the vasculature. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「KRIT1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.