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CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9332 )〕 CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone.〔CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin. Schaer DJ, Schaer CA, Buehler PW, Boykins RA, Schoedon G, Alayash AI, Schaffner A. Blood. 2006 Jan 1;107(1):373-80. PMID 16189277 〕 It has also been shown to mark cells of monocyte/macrophage lineage. The receptor was discovered in 1987. == Structure == The molecular size is 130 kDa. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CD163」の詳細全文を読む スポンサード リンク
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