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CD1D : ウィキペディア英語版
CD1D

CD1D is the human gene that encodes the protein CD1d,〔(【引用サイトリンク】url=http://www.uniprot.org/uniprot/P15813 )〕 a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules.
==Biological significance==

CD1d-presented lipid antigens activate a special class of T cells, known as natural killer T (NKT) cells, through the interaction with the T-cell receptor present on NKT membranes.〔 When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and interleukin 4 production.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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