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CD226
CD226 (Cluster of Differentiation 226), PTA1 (outdated term, 'platelet and T cell activation antigen 1') or DNAM-1 (DNAX Accessory Molecule-1)〔 is a protein that in humans is encoded by the ''CD226'' gene which is located on chromosome 18q22.3.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10666 )〕 == Structure and function ==
CD226 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking CD226 with antibodies causes cellular activation.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CD226」の詳細全文を読む
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