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T-cell surface glycoprotein CD3 epsilon chain
CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the ''CD3E'' gene which resides on chromosome 11.
== Function ==
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=916 )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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