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CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino acids. LAT is highly expressed in brain capillaries (which form the blood–brain barrier) relative to other tissues.〔 A functional LAT1 transporter is composed of two proteins encoded by two distinct genes: * 4F2hc/CD98 heavy subunit protein encoded by the SLC3A2 gene * CD98 light subunit protein encoded by the SLC7A5 gene ==See also== * Cluster of differentiation * Transmembrane protein * Transport protein * Solute carrier family 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CD98」の詳細全文を読む スポンサード リンク
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