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CDC42EP2
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CDC42EP2 : ウィキペディア英語版
CDC42EP2

Cdc42 effector protein 2 is a protein that in humans is encoded by the ''CDC42EP2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10435 )
== Function ==

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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