|
CEPP is an acronym for the name of a chemotherapy regimen that is intended for treatment of aggressive Non-Hodgkin Lymphomas. Unlike CHOP, this chemotherapy regimen does not contain doxorubicin or any other anthracycline. Thus, it can be used in patients with severe cardiovascular diseases and contraindications for doxorubicin-containing regimens. There are 2 modifications of CEPP - with the addition of bleomycin, called CEPP (B), and without bleomycin - ordinary CEPP.〔(CEPP (B): an effective and well-tolerated regimen in poor-risk, aggressive non-Hodgkin's lymphoma )〕 This regimen also does not contain vincristine and can be used in patients with neuropathy. In combination with anti-CD20, monoclonal, antibody, and rituximab. this regimen is called R-CEPP(B). ()-CEPP(B) regimen consists of: # (R)ituximab - a monoclonal antibody that is able to kill CD20-positive B cells, either normal or malignant; # (C)yclophosphamide - an alkylating antineoplastic agent; # (E)toposide - a topoisomerase inhibitor from the epipodophyllotoxin group; # (P)rocarbazine - an alkylating antineoplastic agent; # (P)rednisone or (P)rednisolone - a glucocorticoid hormone that has the ability to cause apoptosis and lysis of lymphocytes, either normal or malignant; # (B)leomycin - an antitumor antibiotic. == Dosing regimen == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CEPP」の詳細全文を読む スポンサード リンク
|