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CGS-21680 : ウィキペディア英語版
CGS-21680

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CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is usually presented as an organic hydrochloride salt with a molecular weight of 536.0 g/''M''. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) ''aq'' 2-hydroxypropyl-β-cyclodextrin.
The chemical is currently used by researchers interested in studying neuronal transmission with a high-affinity, subtype specific analogue for adenosine. This includes research in respiration where it is believed that A2A receptors are involved in rhythm generation in the pre-Bötzinger complex. The drug is not currently approved for use in a therapeutic capacity.
==See also==

* Adenosine receptor

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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