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CKAP5
Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the ''CKAP5'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9793 )〕 It is the homolog of the ''Xenopus'' protein XMAP215 and is also known as ch-Tog. It has at least two distinct roles in spindle formation: it protects kinetochore microtubules from depolymerization by MCAK (KIF2C), and ch-Tog plays an essential role in centrosomal microtubule assembly, a function independent of MCAK activity. == Interactions ==
CKAP5 has been shown to interact with TACC1.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CKAP5」の詳細全文を読む
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