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Coronin, actin binding protein, 1B also known as CORO1B is a protein which in humans is encoded by the ''CORO1B'' gene. Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility. == Function == A mammalian coronin enriches at the leading edge of migrating cells.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57175 )〕 Studies related to this protein are as follows: * Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia. * F-actin binding is essential for coronin 1B function in vivo. * Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. * Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility.〔 * In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury. * Isolation, cloning, and characterization of a new mammalian coronin family member, coroninse, which is regulated within the protein kinase C signaling pathway. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CORO1B」の詳細全文を読む スポンサード リンク
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