|
CP-132,484 is a tryptamine derivative which acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors.〔Macor JE, Fox CB, Johnson C, Koe BK, Lebel LA, Zorn SH. 1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano()indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors. ''Journal of Medicinal Chemistry''. 1992 Oct 2;35(20):3625-32. PMID 1433172〕 It has reasonable selectivity for 5-HT2A and 5-HT2C subtypes over 5-HT2B, but is only slightly selective for 5-HT2A over 5-HT2C. This compound and several related analogues have been shown to have ocular hypotensive activity in animal models, suggesting they may be useful for the treament of glaucoma. ==See also== * AL-37350A * AL-38022A * 1-Methylpsilocin * 4,5-DHP-DMT 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CP-132,484」の詳細全文を読む スポンサード リンク
|