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CRLF3 Cytokine receptor-like factor 3 is a protein that in humans is encoded by the ''CRLF3'' gene. ==Model organisms==
Model organisms have been used in the study of CRLF3 function. A conditional knockout mouse line, called ''Crlf3tm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program, a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty six tests were carried out and two significant phenotypes were reported. Homozygous mutant female adults had a significant increase in circulating levels of fructosamine, while mutants of both sexes had decreased platelet cell numbers.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「CRLF3」の詳細全文を読む
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