翻訳と辞書 Words near each other ・ Cry! – Tender ・ Cry, Cry, Cry (Connie Smith song) ・ Cry, Cry, Cry (Highway 101 song) ・ Cry, Onion! ・ Cry, the Beloved Country ・ Cry, the Beloved Country (1951 film) ・ Cry, the Beloved Country (1995 film) ・ Cry, the Beloved Country (disambiguation) ・ Cry, Yonne ・ Cry-Baby ・ Cry-Baby (musical) ・ Cry1Ac ・ Cry3Bb1 ・ Crya ・ CRYAA ・ CRYAB ・ Cryan ・ Cryan (disambiguation) ・ Cryassa ・ CRYBA4 ・ Crybaby ・ Crybaby (song) ・ Crybaby Bridge ・ CRYBB1 ・ CRYBB2 ・ CRYBB3 ・ Crychan Forest Tracks ・ Crychan Formation ・ Crydamoure ・ Crydee Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク CRYAB ： ウィキペディア英語版 CRYAB Alpha-crystallin B chain is a protein that in humans is encoded by the ''CRYAB'' gene. It is part of the small heat shock protein family and functions as molecular chaperone that primarily binds misfolded proteins to prevent protein aggregation, as well as inhibit apoptosis and contribute to intracellular architecture.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1410 )〕 Post-translational modifications decrease the ability to chaperone.〔〔 Defects in this gene/protein have been associated with cancer and neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.〔〔〔 == Structure == Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CRYAB」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.