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CSRP3
Cysteine and glycine-rich protein 3 gene codes for the Muscle LIM Protein (MLP) or CSRP3, a small 194 amino acid protein, which is specifically expressed in skeletal muscles and cardiac muscle. Since the identification of MLP, 20 years ago, a multitude of studies have focused on delineating its functional significance. == Gene == The CSRP3 gene was discovered in rat in 1994.〔 In humans it was mapped to chromosome 11p15.1, where it spans a 20kb genomic region, organized in 6 exons. The full length transcript is 0.8kb,〔 while a splice variant, originating from the alternative splicing of exons 3 and 4, was recently identified and designated MLP-b.
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