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・ Cypho purpurascens
・ Cyornis
・ CYP
・ CYP17A1
・ CYP1A2
・ CYP1B1
・ CYP20A1
・ CYP24A1
・ CYP26A1
・ CYP26B1
・ CYP26C1
・ CYP27A1
・ CYP27C1
・ CYP2A
・ CYP2A13
CYP2A6
・ CYP2A7
・ CYP2B6
・ CYP2C18
・ CYP2C19
・ CYP2C8
・ CYP2C9
・ CYP2C9*13
・ CYP2C9*3
・ CYP2D6
・ CYP2E1
・ CYP2F1
・ CYP2J2
・ CYP2R1
・ CYP2S1


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CYP2A6 : ウィキペディア英語版
CYP2A6

Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. CYP2A6 is the primary enzyme responsible for the oxidation of nicotine and cotinine. It is also involved in the metabolism of several pharmaceuticals, carcinogens, and a number of coumarin-type alkaloids. CYP2A6 is the only enzyme in the human body that appreciably catalyzes the 7-hydroxylation of coumarin, such that the formation of the product of this reaction, 7-hydroxycoumarin, is used as a probe for CYP2A6 activity.
The CYP2A6 gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1548 )
== Interactive pathway map ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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